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QPC Proteomics Platforms and Instruments

Platforms available at QPC across LC–MS, spatial imaging, and front-end sample processing.

At a glance​

LC–MS proteomics

Discovery and targeted workflows for quantitative proteomics and interaction studies.

Imaging mass spectrometry

Spatially resolved molecular profiling directly from tissue sections (MALDI).

Sample processing

Front-end tools for reproducible tissue disruption and sample preparation.

Liquid chromatography–mass spectrometry (LC–MS)​

High-resolution LC–MS systems support quantitative proteomics and interaction studies, spanning discovery-oriented and targeted applications. Methods and instrument configurations are tailored to study design and sample constraints.

  • Bruker timsTOF fleX mass spectrometer — tims separation + PASEF-enabled proteomics.
  • Thermo Fisher Scientific Q Exactive HF mass spectrometer — Orbitrap-based high-resolution LC–MS for discovery and targeted quantification.
  • Evosep One liquid chromatography system — robust, higher-throughput LC suitable for consistent large-batch runs.

Imaging mass spectrometry​

Imaging mass spectrometry supports spatially resolved analyses and tissue-based studies where localisation is part of the biological question.

  • Bruker timsTOF fleX MALDI — MALDI-based imaging workflows for spatial molecular profiling.

Sample processing​

Front-end instrumentation supports reproducible sample preparation from tissues and complex samples prior to mass spectrometry analysis.

  • Bruker BeatBox tissue homogenizer — reproducible tissue disruption prior to lysis and downstream proteomics workflows.